Sunday, March 7, 2021

Scientists underestimated the coronavirus — and are racing to keep up with evolution

By Carolyn Y. Johnson, The Washington Post

March 7, 2021 -- Evolutionary biologist Jesse Bloom knew it was only a matter of time: The coronavirus would turn into an even more formidable foe, able to dodge the disease-fighting antibodies that protect people after being infected or vaccinated.

More at:

https://www.msn.com/en-us/health/medical/scientists-underestimated-the-coronavirus-and-are-racing-to-keep-up-with-evolution/ar-BB1ekNbq?ocid=msedgdhp

Saturday, March 6, 2021

Vegan Diet and Bone Health Tested

Comparative study shows differences in bone health

From: the German Federal Institute for Risk Assessment (BfR)

March 1, 2021 -- The vegan diet is on trend. How this type of diet affects health is the subject of scientific studies. In a new study from the BfR, the bone health of 36 vegans as well as 36 people following a mixed-food diet was determined with an ultrasound measurement of the heel bone. The result: on average, people following a vegan diet had lower ultrasound values compared to the other group. This indicates poorer bone health. In the study, the scientists also determined biomarkers in blood and urine. This aims to identify nutrients that might be related to diet and bone health. Out of 28 parameters of nutritional status and bone metabolism, it was possible to identify twelve biomarkers most strongly associated with bone health - for example, the amino acid lysine and vitamins A and B6. The results show that in most cases, the combination of these biomarkers was present in lower concentrations in vegans. This could be a possible explanation for the poorer bone health. "A vegan diet is often considered health-conscious. However, our scientific findings indicate that a vegan diet does affect bone health," says BfR President Professor Dr. Dr. Andreas Hensel.

Nutrition plays an important role in bone health. This was more closely investigated in the BfR’s cross-sectional “Risks and benefits of a vegan diet” study. 72 men and women participated in the study. The bone health of all participants was assessed at the heel bone using ultrasound measurements. Information on age, smoking status, education, body mass index, physical activity and alcohol consumption was also collected. By using a statistical model, the BfR was able to identify a pattern of twelve biomarkers that play an important role in bone health from 28 nutrition- and bone-relevant parameters from blood or urine. It was shown that in combination vitamins A and B6, the amino acids lysine and leucine, omega-3 fatty acids, selenoprotein P, iodine, thyroid-stimulating hormone, calcium, magnesium and α-Klotho protein were positively associated with bone health. Conversely, lower concentrations of the hormone FGF23 were observed at higher ultrasound levels in this pattern.

Taking into account other scientific studies, the results indicate that vegans intake fewer nutrients that are relevant for the skeleton and are mainly found in food of animal origin. Further studies are needed for clarification.

About the BfR

The German Federal Institute for Risk Assessment (BfR) is a scientifically independent institution within the portfolio of the Federal Ministry of Food and Agriculture (BMEL) in Germany. It advises the German federal government and German federal states ("Laender") on questions of food, chemical and product safety. The BfR conducts its own research on topics that are closely linked to its assessment tasks.

This text version, https://www.bfr.bund.de/en/press_information/2021/09/does_a_vegan_diet_lead_to_poorer_bone_health_-268536.html, is a translation of the original German text which is the only legally binding version.

Link to publication:

https://www.mdpi.com/2072-6643/13/2/685/htm

Friday, March 5, 2021

Fruits and Vegetables for Longer Life

The right '5-a-day' mix is 2 fruit and 3 vegetable servings

From: The American Heart Association

March 1, 2021 -- According to new research published today in the American Heart Association's flagship journal Circulation, diets rich in fruits and vegetables help reduce risk for numerous chronic health conditions that are leading causes of death, including cardiovascular disease and cancer. Yet, only about one in 10 adults eat enough fruits or vegetables, according to the U.S. Centers for Disease Control and Prevention.

"While groups like the American Heart Association recommend four to five servings each of fruits and vegetables daily, consumers likely get inconsistent messages about what defines optimal daily intake of fruits and vegetables such as the recommended amount, and which foods to include and avoid," said lead study author Dong D. Wang, M.D., Sc.D., an epidemiologist, nutritionist and a member of the medical faculty at Harvard Medical School and Brigham and Women's Hospital in Boston.

Wang and colleagues analyzed data from the Nurses' Health Study and the Health Professionals Follow-Up Study, two studies including more than 100,000 adults who were followed for up to 30 years. Both datasets included detailed dietary information repeatedly collected every two to four years. For this analysis, researchers also pooled data on fruit and vegetable intake and death from 26 studies that included about 1.9 million participants from 29 countries and territories in North and South America, Europe, Asia, Africa and Australia.

Analysis of all studies, with a composite of more than 2 million participants, revealed:

  • Intake of about five servings of fruits and vegetables daily was associated with the lowest risk of death. Eating more than five servings was not associated with additional benefit.
  • Eating about two servings daily of fruits and three servings daily of vegetables was associated with the greatest longevity.
  • Compared to those who consumed two servings of fruit and vegetables per day, participants who consumed five servings a day of fruits and vegetable had a 13% lower risk of death from all causes; a 12% lower risk of death from cardiovascular disease, including heart disease and stroke; a 10% lower risk of death from cancer; and a 35% lower risk of death from respiratory disease, such as chronic obstructive pulmonary disease (COPD).
  • Not all foods that one might consider to be fruits and vegetables offered the same benefits. For example: Starchy vegetables, such as peas and corn, fruit juices and potatoes were not associated with reduced risk of death from all causes or specific chronic diseases.
  • On the other hand, green leafy vegetables, including spinach, lettuce and kale, and fruit and vegetables rich in beta carotene and vitamin C, such as citrus fruits, berries and carrots, showed benefits.

"Our analysis in the two cohorts of U.S. men and women yielded results similar to those from 26 cohorts around the world, which supports the biological plausibility of our findings and suggests these findings can be applied to broader populations," Wang said.

Wang said this study identifies an optimal intake level of fruits and vegetables and supports the evidence-based, succinct public health message of '5-a-day,' meaning people should ideally consume five servings of fruit and vegetable each day. "This amount likely offers the most benefit in terms of prevention of major chronic disease and is a relatively achievable intake for the general public," he said. "We also found that not all fruits and vegetables offer the same degree of benefit, even though current dietary recommendations generally treat all types of fruits and vegetables, including starchy vegetables, fruit juices and potatoes, the same."

A limitation of the research is that it is observational, showing an association between fruit and vegetable consumption and risk of death; it does not confer a direct cause-and-effect relationship.

"The American Heart Association recommends filling at least half your plate with fruits and vegetables at each meal," said Anne Thorndike, M.D., M.P.H., chair of the American Heart Association's nutrition committee and an associate professor of medicine at Harvard Medical School in Boston. "This research provides strong evidence for the lifelong benefits of eating fruits and vegetables and suggests a goal amount to consume daily for ideal health. Fruits and vegetables are naturally packaged sources of nutrients that can be included in most meals and snacks, and they are essential for keeping our hearts and bodies healthy."

Co-authors are Yanping Li, Ph.D.; Shilpa N. Bhupathiraju, Ph.D.; Bernard A. Rosner, Ph.D.; Qi Sun, M.D., Sc.D.; Edward L. Giovannucci; Eric B. Rimm, Sc.D.; JoAnn E. Manson, M.D., M.P.H., Dr.P.H., FAHA; Walter C. Willett, M.D., Dr.P.H.; Meir J. Stampfer, M.D., Dr.P.H.; and Frank B. Hu, M.D., Ph.D.

The study was funded by the National Institutes of Health, the American Heart Association and the National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health.

         https://www.sciencedaily.com/releases/2021/03/210301084519.htm

Thursday, March 4, 2021

A Prediction of Colder Winters

By Richard Schulman, Editor of Founders Broadsheet

 

“Astonishing as it may seem, the physics of two primary determinants of earth’s climate — sun and clouds — is poorly incorporated into the climate models upon which the Biden administration’s trillion-dollar green-energy spending blowout is based. This is the greatest scandal in the history of science…”

—March 3, 2021

https://foundersbroadsheet.com/ 

Wednesday, March 3, 2021

Particles Emerge As Two Photons Couple

Researchers exploring the interactions between light particles, photons and matter find that optical microresonators host quasiparticles made by two photons.

From: University of Bath

March 2, 2021 -- Scientists at the University of Bath have found a way to bind together two photons of different colors, paving the way for important advancements in quantum-electrodynamics – the field of science that describes how light and matter interact. In time, the team’s findings are likely to impact developments in optical and quantum communication, and precision measurements of frequency, time and distances.

Apple and wave: they both have a mass

An apple falling from a tree has velocity and mass, which together give it momentum. ‘Apple energy’ derived from motion depends on the fruit’s momentum and mass.

Most people find the concept of momentum and energy (and therefore mass) an easy one to grasp when it’s associated with solid objects. But the idea that non-material objects, such as light waves (everything from sunlight to laser radiation), also have a mass is surprising to many. Among physicists, however, it’s a well-known fact. This apparently paradoxical idea that waves have a mass marks the place where quantum physics and the physical world come together.

The wave-particle duality, proposed by French physicist Louis de Broglie in 1924, is a powerful concept that describes how every particle or quantum entity can be described as either a particle or a wave. Many so-called quasiparticles have been discovered that combine either two different types of matter particles, or light waves bound to a particle of matter. A list of exotic quasiparticles includes phonons, plasmons, magnons and polaritons.

The team of physicists at Bath has now reported a way to create quasiparticles that bind together two differently colored particles of light. They have named these formations photon-photon polaritons.

Detecting photon-photon polaritons

The opportunity to discover, and manipulate, photon-photons is possible thanks to the relatively new development of high-quality microresonators. For light, microresonators act as miniature racetracks, with photons zipping around the internal structure in loops. The signature left by photon-photons in the light exiting the microresonator can be linked to the Autler–Townes effect, a peculiar phenomenon in quantum theory that describes strong photon-atom interactions. To achieve this effect in microresonators, a laser is tuned to the specific resonance frequency where a photon is expected to be absorbed, yet no resonance absorption happens. Instead, the photon-photon interaction makes up two new resonance frequencies away from the old one.

A significant feature that has emerged from the Bath research is that the microresonator provided a whole set of split resonances, where each photon-photon pair displayed its own momentum and energy, allowing the researchers to apply the quasiparticle concept and calculate mass. According to the researchers’ predictions, photon-photons are 1,000+ times lighter than electrons.

Professor Dmitry Skryabin, the physicist who led the research, said: "We now have a situation where microresonators – which are millimeter-scale objects – behave like giant atoms. The artificial atoms concept is rapidly gaining ground in the quantum-electrodynamics of microwaves in superconducting circuits, while here we are looking at the similar opportunity in the optical range of frequencies.

“The small mass of photon-photons could lead to further developments of many important analogies between light and fluids, where other families of quasiparticles have already been used."

PhD student Vlad Pankratov, who participated in the project, said: “After a year of running models and collecting data, these are incredibly exciting findings for us. The potential applications of our results are in the terabit and quantum optical communication schemes, and in the area of precision measurements."

This work was supported by the European Union Marie Skłodowska-Curie Actions (812818, MICROCOMB)

The paper Photon-photon polaritons in χ(2) microresonators is published in Physical Review Research.

https://www.bath.ac.uk/announcements/photon-photon-polaritons-the-intriguing-particles-that-emerge-when-two-photons-couple/

= = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = =

An optical microcavity or microresonator is a structure formed by reflecting faces on the two sides of a spacer layer or optical medium, or by wrapping a waveguide in a circular fashion to form a ring. The former type is a standing wave cavity, and the latter is a traveling wave cavity. The name microcavity stems from the fact that it is often only a few micrometers thick, the spacer layer sometimes even in the nanometer range. As with common lasers this forms an optical cavity or optical resonator, allowing a standing wave to form inside the spacer layer, or a traveling wave that goes around in the ring.

                        https://en.wikipedia.org/wiki/Optical_microcavity

 

Monday, March 1, 2021

Reducing Collusion Among Online Students

In era of online learning, new testing method aims to reduce cheating

From:  Rensselaer Polytechnic Institute

Troy, New York – March 1, 2021 -- The era of widespread remote learning brought about by the COVID-19 pandemic requires online testing methods that effectively prevent cheating, especially in the form of collusion among students. With concerns about cheating on the rise across the country, a solution that also maintains student privacy is particularly valuable.

In research published today in npj Science of Learning, engineers from Rensselaer Polytechnic Institute demonstrate how a testing strategy they call "distanced online testing" can effectively reduce students' ability to receive help from one another in order to score higher on a test taken at individual homes during social distancing.

"Often in remote online exams, students can talk over the phone or internet to discuss answers," said Ge Wang, an endowed chair professor of biomedical engineering at Rensselaer and the corresponding author on this paper. "The key idea of our method is to minimize this chance via discrete optimization aided by knowledge of a student's competencies."

When a distanced online test is performed, students receive the same questions, but at varying times depending on their skill level. For instance, students of highest mastery levels receive each question after other groups of students have already answered those questions. This approach, Wang said, reduces the incentive for students to receive help from those who have more mastery of the material. In order to determine the order of each student's questions, their competence levels are estimated using their grade point averages, SAT scores, or midterm scores, depending on what is available at a specific point in the semester.

According to statistical tests and post-exam surveys, this method reduced the points gained through collusion by orders of magnitude when compared to conventional exam methods. As an added benefit, Wang said, when students knew collusion would not be possible, they were more motivated to study class material. Wang and his collaborators hope to share this pedagogical innovation beyond the Rensselaer campus.

"We plan to develop a good platform so that others can easily use this method," said Wang, a member of the Center for Biotechnology and Interdisciplinary Studies at Rensselaer.

In era of online learning, new testing method aims to reduce cheating: New method proven effective in reducing collusion among students -- ScienceDaily