Rose Marie Mazetta was born in
She performed at the opening night of the Flamingo Hotel, which was built by Siegel. At her height of fame as a child singer, from late 1929 to 1934, she had her own radio show, made numerous records, and was featured in a number of
In 1929, the five- or six-year-old singer made a Vitaphone sound short titled "Baby Rose Marie the Child Wonder", now restored and available in the Warner Bros. DVD set of The Jazz Singer. She continued to appear in films through the mid-1930s, making shorts and a feature, International House (1933), with W. C. Fields for
Between 1930 and 1938, she made 17 recordings, three of which were unissued. Her first issued record, recorded on March 10, 1932, featured accompaniment by Fletcher Henderson's band, one of the premier black jazz orchestras. According to Hendersonia, the bio-discography by Walter C. Allen,
Her recording "Say That You Were Teasing Me" (b/w "Take a Picture of the Moon; Victor 22960) also featured
In the 1960–61 season, Rose Marie costarred with Shirley Bonne, Elaine Stritch, Jack Weston, Raymond Bailey, and Stubby Kaye in the CBS sitcom My Sister Eileen. She played Bertha, a friend of the Sherwood sisters: Ruth, a magazine writer, played by Stritch, and Eileen, an aspiring actress, Bonne's role.
After five seasons (1961–1966) of The Dick Van Dyke Show, Rose Marie costarred in two seasons (1969–1971) of CBS's The Doris Day Show as Doris Martin's friend and coworker, Myrna Gibbons. She also appeared in two episodes of the NBC series The Monkees in the mid-1960s. She later had a semiregular seat in the upper center square on the original version of Hollywood Squares, alongside her friend and longtime Dick Van Dyke co-star, Morey Amsterdam. She also appeared on both the 1986 and 1998 syndicated revivals.
In the early 1990s, she had a recurring role as Frank Fontana's mother on the CBS sitcom Murphy Brown. She appeared as Roy Biggins's domineering mother, Eleanor "Bluto" Biggins, in an episode of the television series Wings. Rose Marie and Morey Amsterdam appeared together in an October 1993 episode of Herman's Head and guest-starred in a February 1996 episode of the NBC sitcom Caroline in the City, shortly before
She appeared with the surviving Dick Van Dyke Show cast members in a 2004 reunion special. Rose Marie was especially close to actor Richard Deacon from that show and offered him the suits left behind when her husband died in 1964, as the two men were of similar height and build.