Current nanoscopic techniques are extremely complex, expensive, and require intensively trained technicians. Up to now, these limitations have restricted the use of nanoscopy to only highly specialized institutes throughout the world and prevented its spread to standard laboratories in biology and medicine let alone to hospitals and analytical laboratories.
The invention of the ‘chip-based nanoscopy’ procedure by researchers at
- In 1609, Galileo Galilei invented light microscopy.
- In 1873, Ernst Abbe discovered the fundamental property that limits the resolution of an optical system for visible light to roughly 250 nanometres.
- In recent years, several optical methods have been developed concurrently in order to overcome the diffraction limit of light. In 2014, the Nobel Prize for Chemistry was awarded for the development of a superresolution in the range of roughly 20 to 30 nanometres.
Diekmann R., Helle Ø.I., Øie C.I., McCourt P., Huser T.R., Schüttpelz M., Ahluwalia B.S.:
Chip-based wide field-of-view nanoscopy, Nature Photonics, http://dx.doi.org/10.1038/nphoton.2017.55, published on the 24th of April 2017