By Morgan Kelly,
Wingreen initiated the project after reading Basler's 2013 paper. That study showed that when P. aeruginosa attacked V. cholerae and the bacteria Acinetobacter baylyi — which also has the T6S system — they only resorted to using T6S when they detected that their targets also were using it. Wingreen began thinking that perhaps the use of T6S is selective and that there are costs and benefits bacteria consider, he said. He approached Borenstein, a software engineer, who had designed a simulation program called Nanoverse that predicts the outcomes of biological processes.